PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35090381-4	2022	We developed an IgG4-type monoclonal antibody against human TIGIT, designated as MG1131, using a phage display library of single-chain variable fragments (scFvs).	mg1131	81-87	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	60-65	
35090381-5	2022	MG1131 interacts with TIGIT much more tightly than PVR does.	mg1131	0-6	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	22-27	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	43-49	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	59-64	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	43-49	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	121-126	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	43-49	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	183-188	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	94-100	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	59-64	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	94-100	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	121-126	
35090381-6	2022	The crystal structure of a scFv version of MG1131 bound to TIGIT was determined, showing that MG1131 could block the PVR-TIGIT interaction and thus the immunosuppressive signaling of TIGIT.	mg1131	94-100	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	183-188	
35090381-7	2022	Consistently, MG1131 is bound to TIGIT-expressing cells and interferes with PVR binding to these cells.	mg1131	14-20	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	33-38