PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35070248-4 2022 BRCA-mutated patients, already treated with platinum-derived drugs, who suffered DNA damage, cannot repair the breaks due to lurbinectedin interaction, whereas irinotecan provokes a dsDNA break that promotes synthetic lethality. Platinum 44-52 BRCA1 DNA repair associated Homo sapiens 0-4