PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35046516-4 2022 Mass spectrometric analysis identified PRMT5 lysine 387 as its succinylation site. Lysine 45-51 protein arginine methyltransferase 5 Homo sapiens 39-44 35046516-5 2022 Moreover, the desuccinylation of PRMT5 K387 enhances the methyltransferase activity of PRMT5. isophorone 39-43 protein arginine methyltransferase 5 Homo sapiens 33-38 35046516-5 2022 Moreover, the desuccinylation of PRMT5 K387 enhances the methyltransferase activity of PRMT5. isophorone 39-43 protein arginine methyltransferase 5 Homo sapiens 87-92 35046516-7 2022 The SIRT7-mediated dessuccinylation of PRMT5 lysine 387 fails to bind to STUB1, decreasing PRMT5 ubiquitination and increasing the interaction between PRMT5 and Mep50, which promotes the formation of the PRMT5-Mep50 octamer. Lysine 45-51 sirtuin 7 Homo sapiens 4-9 35046516-7 2022 The SIRT7-mediated dessuccinylation of PRMT5 lysine 387 fails to bind to STUB1, decreasing PRMT5 ubiquitination and increasing the interaction between PRMT5 and Mep50, which promotes the formation of the PRMT5-Mep50 octamer. Lysine 45-51 protein arginine methyltransferase 5 Homo sapiens 39-44 35046516-7 2022 The SIRT7-mediated dessuccinylation of PRMT5 lysine 387 fails to bind to STUB1, decreasing PRMT5 ubiquitination and increasing the interaction between PRMT5 and Mep50, which promotes the formation of the PRMT5-Mep50 octamer. Lysine 45-51 WD repeat domain 77 Homo sapiens 161-166 35046516-8 2022 The PRMT5-Mep50 octamer increases PRMT5 methyltransferase activity, leading to arginine methylation of SREBP1a. Arginine 79-87 protein arginine methyltransferase 5 Homo sapiens 4-9 35046516-8 2022 The PRMT5-Mep50 octamer increases PRMT5 methyltransferase activity, leading to arginine methylation of SREBP1a. Arginine 79-87 WD repeat domain 77 Homo sapiens 10-15 35046516-8 2022 The PRMT5-Mep50 octamer increases PRMT5 methyltransferase activity, leading to arginine methylation of SREBP1a. Arginine 79-87 protein arginine methyltransferase 5 Homo sapiens 34-39 35046516-8 2022 The PRMT5-Mep50 octamer increases PRMT5 methyltransferase activity, leading to arginine methylation of SREBP1a. Arginine 79-87 sterol regulatory element binding transcription factor 1 Homo sapiens 103-110 35046516-9 2022 The symmetric dimethylation of SREBP1a increases the levels of cholesterol, fatty acid, and triglyceride biogenesis in the cells, escaping degradation through the ubiquitin-proteasome pathway. Cholesterol 63-74 sterol regulatory element binding transcription factor 1 Homo sapiens 31-38 35046516-9 2022 The symmetric dimethylation of SREBP1a increases the levels of cholesterol, fatty acid, and triglyceride biogenesis in the cells, escaping degradation through the ubiquitin-proteasome pathway. Fatty Acids 76-86 sterol regulatory element binding transcription factor 1 Homo sapiens 31-38 35046516-9 2022 The symmetric dimethylation of SREBP1a increases the levels of cholesterol, fatty acid, and triglyceride biogenesis in the cells, escaping degradation through the ubiquitin-proteasome pathway. Triglycerides 92-104 sterol regulatory element binding transcription factor 1 Homo sapiens 31-38