PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34943075-11 2021 Furthermore, the Rg3-reverted SIRT1/PGC-1alpha/SIRT3 activation mediated the repression of p38 MAPK, which downregulated the NF-kappaB translocation in the TNF-alpha-treated cells. ginsenoside Rg3 17-20 nuclear factor kappa B subunit 1 Homo sapiens 125-134 34943075-12 2021 Our results revealed that administration of Rg3 diminished the production of interleukin 8 (IL-8) and matrix metallopeptidase 9 (MMP-9) in chondrocytes via SIRT1/PGC-1alpha/SIRT3/p38 MAPK/NF-kappaB signaling in response to TNF-alpha stimulation. ginsenoside Rg3 44-47 nuclear factor kappa B subunit 1 Homo sapiens 188-197