PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34925523-0 2021 Breviscapine Participates in the Progression of Prostate Cancer by Inhibiting ZFP91 Expression through Upregulation of MicroRNA-129-5p. breviscapine 0-12 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 78-83 34925523-0 2021 Breviscapine Participates in the Progression of Prostate Cancer by Inhibiting ZFP91 Expression through Upregulation of MicroRNA-129-5p. breviscapine 0-12 microRNA 1295a Homo sapiens 119-134 34925523-3 2021 In addition, the binding of microRNA-129-5p and ZFP91 was confirmed by dual-luciferase reporting assay; meanwhile, cell reverse experiment verified that breviscapine can regulate ZFP91 via upregulating microRNA-129-5p. breviscapine 153-165 microRNA 1295a Homo sapiens 28-43 34925523-3 2021 In addition, the binding of microRNA-129-5p and ZFP91 was confirmed by dual-luciferase reporting assay; meanwhile, cell reverse experiment verified that breviscapine can regulate ZFP91 via upregulating microRNA-129-5p. breviscapine 153-165 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 48-53 34925523-3 2021 In addition, the binding of microRNA-129-5p and ZFP91 was confirmed by dual-luciferase reporting assay; meanwhile, cell reverse experiment verified that breviscapine can regulate ZFP91 via upregulating microRNA-129-5p. breviscapine 153-165 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 179-184 34925523-3 2021 In addition, the binding of microRNA-129-5p and ZFP91 was confirmed by dual-luciferase reporting assay; meanwhile, cell reverse experiment verified that breviscapine can regulate ZFP91 via upregulating microRNA-129-5p. breviscapine 153-165 microRNA 1295a Homo sapiens 202-217 34925523-4 2021 Results: The results of MTT, CCK-8, and Transwell experiments demonstrated that breviscapine inhibited the proliferation as well as the migration capacities of PC cells; meanwhile, it upregulated the level of microRNA-129-5p in PC cells while downregulated that of ZFP91. breviscapine 80-92 microRNA 1295a Homo sapiens 209-224 34925523-4 2021 Results: The results of MTT, CCK-8, and Transwell experiments demonstrated that breviscapine inhibited the proliferation as well as the migration capacities of PC cells; meanwhile, it upregulated the level of microRNA-129-5p in PC cells while downregulated that of ZFP91. breviscapine 80-92 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 265-270 34925523-6 2021 Finally, cell reverse experiment confirmed that breviscapine downregulated ZFP91 expression by upregulating microRNA-129-5p, while downregulation of microRNA-129-5p partially reversed the inhibitory effect of breviscapine on cell proliferation ability. breviscapine 48-60 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 75-80 34925523-6 2021 Finally, cell reverse experiment confirmed that breviscapine downregulated ZFP91 expression by upregulating microRNA-129-5p, while downregulation of microRNA-129-5p partially reversed the inhibitory effect of breviscapine on cell proliferation ability. breviscapine 48-60 microRNA 1295a Homo sapiens 108-123 34925523-6 2021 Finally, cell reverse experiment confirmed that breviscapine downregulated ZFP91 expression by upregulating microRNA-129-5p, while downregulation of microRNA-129-5p partially reversed the inhibitory effect of breviscapine on cell proliferation ability. breviscapine 209-221 microRNA 1295a Homo sapiens 149-164 34925523-7 2021 Conclusions: Breviscapine may inhibit the expression of ZFP91 through upregulating microRNA-129-5p and thus participating in the progression of PC. breviscapine 13-25 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase Homo sapiens 56-61 34925523-7 2021 Conclusions: Breviscapine may inhibit the expression of ZFP91 through upregulating microRNA-129-5p and thus participating in the progression of PC. breviscapine 13-25 microRNA 1295a Homo sapiens 83-98