PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34871844-0	2022	Synthesis and biological evaluation of novel PET tracers (18F)AG120 & (18F)AG135 for imaging mutant isocitrate dehydrogenase 1 expression.	ivosidenib	62-67	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	100-126	
34871844-6	2022	Furthermore, (18F)AG120 micro-PET/CT imaging displayed significantly greater uptake in IDH1-mutant than in wild-type tumors, Relatively, uptake of (18F)AG135 was observed neither in IDH1-mutant tumor xenografts nor in wild-type tumors.	ivosidenib	18-23	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	87-91	
34871844-7	2022	This study suggests that (18F)AG120 is a promising radiotracer for PET imaging of IDH1 mutation, However, further optimization and investigation are necessary for (18F)AG135 due to the limited uptake in mutated IDH1-expressing tumors.	ivosidenib	30-35	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	82-86