PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34857740-5 2021 Following loss- and gain-of-function experiments, in vitro assays in high glucose-treated Schwann cells (SC4) and in vivo assays in db/db and ob/ob mice were performed to detect the effects of PIAS1 on autophagy and apoptosis of Schwann cells as well as symptoms of DPN by regulating the PPAR-gamma-miR-124-EZH2/STAT3. Glucose 74-81 protein inhibitor of activated STAT 1 Mus musculus 193-198