PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34697748-0	2021	Andrographolide Induces Apoptosis in Gastric Cancer Cells through Reactivation of p53 and Inhibition of Mdm-2.	andrographolide	0-15	tumor protein p53	Homo sapiens	82-85	
34697748-6	2021	Effect of andrographolide on p53 activity was ascertained by using a p53 activator (RITA) which showed synergistic inhibition of cell proliferation.	andrographolide	10-25	tumor protein p53	Homo sapiens	29-32	
34697748-7	2021	While andrographolide when used in combination with a p53 inhibitor (pifithrin-alpha) showed potent restriction over its response.	andrographolide	6-21	tumor protein p53	Homo sapiens	54-57	
34697748-9	2021	Andrographolide activated the expression of p53 protein and gene and downregulated the levels of Mdm-2 (negative regulator of p53).	andrographolide	0-15	tumor protein p53	Homo sapiens	44-47	
34697748-9	2021	Andrographolide activated the expression of p53 protein and gene and downregulated the levels of Mdm-2 (negative regulator of p53).	andrographolide	0-15	tumor protein p53	Homo sapiens	126-129	
34697748-10	2021	Andrographolide inhibited the colony formation abilities in SGC7901 in a p53-dependent manner followed by induction of mitochondrial intrinsic apoptosis through activation of caspases-9 and -3, cleavage of PARP, and inhibition of pro-apoptotic Bcl-2.	andrographolide	0-15	tumor protein p53	Homo sapiens	73-76	
34697748-11	2021	Andrographolide induced p53 mediated apoptosis in gastric carcinoma cells which adds to a novel approach in anticancer therapies.	andrographolide	0-15	tumor protein p53	Homo sapiens	24-27