PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34680068-4 2021 The modeling of SCD1:fatty acid interactions suggests that: (1) SCD1:CoA moiety interactions open the substrate-binding tunnel, (2) SCD1 stabilizes a substrate conformation favorable for desaturation, and (3) SCD1:product interactions result in an opening of the tunnel, possibly allowing product exit into the surrounding membrane. Fatty Acids 21-31 stearoyl-CoA desaturase Homo sapiens 16-20 34680068-4 2021 The modeling of SCD1:fatty acid interactions suggests that: (1) SCD1:CoA moiety interactions open the substrate-binding tunnel, (2) SCD1 stabilizes a substrate conformation favorable for desaturation, and (3) SCD1:product interactions result in an opening of the tunnel, possibly allowing product exit into the surrounding membrane. Fatty Acids 21-31 stearoyl-CoA desaturase Homo sapiens 64-68 34680068-4 2021 The modeling of SCD1:fatty acid interactions suggests that: (1) SCD1:CoA moiety interactions open the substrate-binding tunnel, (2) SCD1 stabilizes a substrate conformation favorable for desaturation, and (3) SCD1:product interactions result in an opening of the tunnel, possibly allowing product exit into the surrounding membrane. Fatty Acids 21-31 stearoyl-CoA desaturase Homo sapiens 132-136 34680068-4 2021 The modeling of SCD1:fatty acid interactions suggests that: (1) SCD1:CoA moiety interactions open the substrate-binding tunnel, (2) SCD1 stabilizes a substrate conformation favorable for desaturation, and (3) SCD1:product interactions result in an opening of the tunnel, possibly allowing product exit into the surrounding membrane. Fatty Acids 21-31 stearoyl-CoA desaturase Homo sapiens 209-213