PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34539418-0	2021	alpha-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXRalpha-AKT Signaling Pathway.	mangostin	0-15	retinoid X receptor alpha	Homo sapiens	96-104	
34539418-0	2021	alpha-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXRalpha-AKT Signaling Pathway.	mangostin	0-15	AKT serine/threonine kinase 1	Homo sapiens	105-108	
34539418-5	2021	Then the effect of alpha-Mangostin on the transcriptional activity of RXRalpha was tested by dual-luciferase reporter gene assay.	mangostin	19-34	retinoid X receptor alpha	Homo sapiens	70-78	
34539418-8	2021	alpha-Mangostin regulates the downstream effectors of the PI3K/AKT signaling pathway by degrading RXRalpha/tRXRalpha.	mangostin	0-15	AKT serine/threonine kinase 1	Homo sapiens	63-66	
34539418-8	2021	alpha-Mangostin regulates the downstream effectors of the PI3K/AKT signaling pathway by degrading RXRalpha/tRXRalpha.	mangostin	0-15	retinoid X receptor alpha	Homo sapiens	98-106	
34539418-9	2021	alpha-Mangostin can trigger PARP cleavage and induce apoptosis, which may be related to the induction of upregulated BAX expression and downregulation of BAD and cleaved caspase-3 expression in MDA-MB-231 cells through blockade of AKT signaling.	mangostin	0-15	collagen type XI alpha 2 chain	Homo sapiens	28-32	
34539418-9	2021	alpha-Mangostin can trigger PARP cleavage and induce apoptosis, which may be related to the induction of upregulated BAX expression and downregulation of BAD and cleaved caspase-3 expression in MDA-MB-231 cells through blockade of AKT signaling.	mangostin	0-15	BCL2 associated X, apoptosis regulator	Homo sapiens	117-120	
34539418-9	2021	alpha-Mangostin can trigger PARP cleavage and induce apoptosis, which may be related to the induction of upregulated BAX expression and downregulation of BAD and cleaved caspase-3 expression in MDA-MB-231 cells through blockade of AKT signaling.	mangostin	0-15	caspase 3	Homo sapiens	170-179	
34539418-9	2021	alpha-Mangostin can trigger PARP cleavage and induce apoptosis, which may be related to the induction of upregulated BAX expression and downregulation of BAD and cleaved caspase-3 expression in MDA-MB-231 cells through blockade of AKT signaling.	mangostin	0-15	AKT serine/threonine kinase 1	Homo sapiens	231-234	
34539418-11	2021	Cyclin D1 was involved in the anticancer effects of alpha-Mangostin on the cell cycle in MDA-MB-231 cells.	mangostin	52-67	cyclin D1	Homo sapiens	0-9	
34539418-12	2021	alpha-Mangostin induces apoptosis, suppresses the migration and invasion of breast cancer cells through the PI3K/AKT signaling pathway by targeting RXRalpha, and cyclin D1 has involved in this process.	mangostin	0-15	AKT serine/threonine kinase 1	Homo sapiens	113-116	
34539418-12	2021	alpha-Mangostin induces apoptosis, suppresses the migration and invasion of breast cancer cells through the PI3K/AKT signaling pathway by targeting RXRalpha, and cyclin D1 has involved in this process.	mangostin	0-15	retinoid X receptor alpha	Homo sapiens	148-156	
34539418-12	2021	alpha-Mangostin induces apoptosis, suppresses the migration and invasion of breast cancer cells through the PI3K/AKT signaling pathway by targeting RXRalpha, and cyclin D1 has involved in this process.	mangostin	0-15	cyclin D1	Homo sapiens	162-171