PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34530866-0	2021	NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1alpha pathway.	ros	115-118	sirtuin 1	Rattus norvegicus	179-184	
34530866-11	2021	In vitro study confirmed that NAD+ administration had protective effects on hypoxia-induced neuroinflammation and mitochondrial damage, as well as ROS production in BV2 microglia via Sirt1/PGC-1alpha pathway.	ros	147-150	sirtuin 1	Rattus norvegicus	183-188	
34530866-13	2021	CONCLUSIONS: NAD+ ameliorated cognitive impairment and dampened neuroinflammation in CCH models in vivo and in vitro, and these beneficial effects were associated with mitochondrial protection and ROS inhibition via activating Sirt1/PGC-1alpha pathway.	ros	197-200	sirtuin 1	Rattus norvegicus	227-232