PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34416343-0 2021 Rescue of BDNF Expression by the Thalamic Parafascicular Nucleus with Chronic Treatment with the mGluR2/3 Agonist LY379268 may Contribute to the LY379268 Rescue of Enkephalinergic Striatal Projection Neurons in R6/2 Huntington"s Disease Mice. LY 379268 114-122 glutamate receptor, metabotropic 2 Mus musculus 97-105 34416343-0 2021 Rescue of BDNF Expression by the Thalamic Parafascicular Nucleus with Chronic Treatment with the mGluR2/3 Agonist LY379268 may Contribute to the LY379268 Rescue of Enkephalinergic Striatal Projection Neurons in R6/2 Huntington"s Disease Mice. LY 379268 145-153 glutamate receptor, metabotropic 2 Mus musculus 97-105 34416343-1 2021 We have found that daily subcutaneous injection with a maximum tolerated dose of the mGluR2/3 agonist LY379268 (20 mg/kg) beginning at 4 weeks of age dramatically improves the motor, neuronal and neurochemical phenotype in R6/2 mice, a rapidly progressing transgenic model of Huntington"s disease (HD). LY 379268 102-110 glutamate receptor, metabotropic 2 Mus musculus 85-93