PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34347342-7 2021 In line with PAH status, pulmonary microvessels in monocrotaline-treated animals demonstrated significant (p<0.05, n=6 per group) upregulation of alphaSMA (two fold) and downregulation of BMPR2 (20%). Monocrotaline 51-64 bone morphogenetic protein receptor type 2 Rattus norvegicus 188-193 34347342-10 2021 MQCM and Western blot analysis showed that monocrotaline-induced ZIP12 upregulation could be partially negated by BMPR2-targeted therapy. Monocrotaline 43-56 bone morphogenetic protein receptor type 2 Rattus norvegicus 114-119 34347342-11 2021 Our results indicate that altered zinc transport/storage and S1P signalling in the monocrotaline-induced PAH rat model are linked to each other, and could be alleviated by BMPR2-targeted therapy. Monocrotaline 83-96 bone morphogenetic protein receptor type 2 Rattus norvegicus 172-177