PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34298684-0 2021 The BET Inhibitor JQ1 Augments the Antitumor Efficacy of Gemcitabine in Preclinical Models of Pancreatic Cancer. gemcitabine 57-68 delta/notch like EGF repeat containing Homo sapiens 4-7 34298684-5 2021 BET inhibitors (JQ1 or I-BET762) + gemcitabine were synergistic in vitro, in Panc1, MiaPaCa2 and Su86 PC cell lines. gemcitabine 35-46 delta/notch like EGF repeat containing Homo sapiens 0-3 34298684-8 2021 Notably, RNA-seq data showed that JQ1 + gemcitabine selectively inhibited HMGCS2 and APOC1 ~6-fold, compared to controls. gemcitabine 40-51 3-hydroxy-3-methylglutaryl-CoA synthase 2 Homo sapiens 74-80 34298684-8 2021 Notably, RNA-seq data showed that JQ1 + gemcitabine selectively inhibited HMGCS2 and APOC1 ~6-fold, compared to controls. gemcitabine 40-51 apolipoprotein C1 Homo sapiens 85-90 34298684-10 2021 IPA data indicated that JQ1 + gemcitabine selectively inhibited the LXR/RXR activation pathway, suggesting the hypothesis that this inhibition may contribute to the observed in vivo efficacy of JQ1 + gemcitabine. gemcitabine 30-41 retinoid X receptor alpha Homo sapiens 72-75 34298684-10 2021 IPA data indicated that JQ1 + gemcitabine selectively inhibited the LXR/RXR activation pathway, suggesting the hypothesis that this inhibition may contribute to the observed in vivo efficacy of JQ1 + gemcitabine. gemcitabine 200-211 retinoid X receptor alpha Homo sapiens 72-75