PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34196005-1 2021 Selumetinib (ARRY-142886), an oral, potent and highly selective allosteric MEK1/2 inhibitor, is approved by the US FDA for the treatment of pediatric patients aged 2 years and older with neurofibromatosis type 1 with symptomatic, inoperable plexiform neurofibromas. AZD 6244 0-11 neurofibromin 1 Homo sapiens 187-211 34196005-1 2021 Selumetinib (ARRY-142886), an oral, potent and highly selective allosteric MEK1/2 inhibitor, is approved by the US FDA for the treatment of pediatric patients aged 2 years and older with neurofibromatosis type 1 with symptomatic, inoperable plexiform neurofibromas. AZD 6244 13-24 neurofibromin 1 Homo sapiens 187-211