PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34178835-11 2021 Results: Oral administration of M. charantia nanoparticles (50 mg/kg) to STZ-induced diabetic untreated rats significantly ((p < 0.05) down-regulated the mRNA expression of Akt, PI3k, TGF-beta, JAK2, STAT3 and upregulated the mRNA expression of PTEN, SOCS3 and SOCS4, thus establishing the role of M. charantia nanoparticles in alleviating DN in diabetic rats. Streptozocin 73-76 Janus kinase 2 Rattus norvegicus 194-198