PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34115964-3 2021 We show that metformin inhibited NLRP3 inflammasome activation and interleukin (IL)-1beta production in cultured and alveolar macrophages along with inflammasome-independent IL-6 secretion, thus attenuating lipopolysaccharide (LPS)- and SARS-CoV-2-induced ARDS. Metformin 13-22 interleukin 6 Homo sapiens 174-178