PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34109683-3	2021	However, the relationship between NR4A1 and DIGO remains unclear.	digo	44-48	nuclear receptor subfamily 4, group A, member 1	Mus musculus	34-39	
34109683-4	2021	We herein investigated the involvement of NR4A1 in DIGO.	digo	51-55	nuclear receptor subfamily 4, group A, member 1	Mus musculus	42-47	
34109683-5	2021	In the DIGO mouse model, CsA inhibited the up-regulation of Nr4a1 expression induced by periodontal disease (PD) in gingival tissue, but not that of Col1a1 and Pai1.	Cyclosporine	25-28	nuclear receptor subfamily 4, group A, member 1	Mus musculus	60-65	
34109683-7	2021	A NR4A1 agonist inhibited the development of GO in DIGO model mice.	digo	51-55	nuclear receptor subfamily 4, group A, member 1	Mus musculus	2-7	
34109683-12	2021	CsA suppressed the TGF-beta-induced translocation of NFATc3 into the nuclei of hGF.	Cyclosporine	0-3	transforming growth factor alpha	Homo sapiens	19-27	
34109683-12	2021	CsA suppressed the TGF-beta-induced translocation of NFATc3 into the nuclei of hGF.	Cyclosporine	0-3	nuclear factor of activated T cells 3	Homo sapiens	53-59	
34109683-12	2021	CsA suppressed the TGF-beta-induced translocation of NFATc3 into the nuclei of hGF.	Cyclosporine	0-3	hepatocyte growth factor	Homo sapiens	79-82	
34109683-14	2021	We confirmed that CsA, NIF, and PHT reduced cytosolic calcium levels increased by TGF-beta, while CaCl2 enhanced the TGF-beta-up-regulated NR4A1 expression.	Cyclosporine	18-21	transforming growth factor alpha	Homo sapiens	82-90	
34109683-14	2021	We confirmed that CsA, NIF, and PHT reduced cytosolic calcium levels increased by TGF-beta, while CaCl2 enhanced the TGF-beta-up-regulated NR4A1 expression.	Cyclosporine	18-21	nuclear receptor subfamily 4 group A member 1	Homo sapiens	139-144	
34109683-14	2021	We confirmed that CsA, NIF, and PHT reduced cytosolic calcium levels increased by TGF-beta, while CaCl2 enhanced the TGF-beta-up-regulated NR4A1 expression.	Calcium	54-61	transforming growth factor alpha	Homo sapiens	82-90	
34109683-14	2021	We confirmed that CsA, NIF, and PHT reduced cytosolic calcium levels increased by TGF-beta, while CaCl2 enhanced the TGF-beta-up-regulated NR4A1 expression.	Calcium Chloride	98-103	nuclear receptor subfamily 4 group A member 1	Homo sapiens	139-144	
34109683-15	2021	We propose that the suppression of the calcium-NFATc3-NR4A1 cascade by these three drugs plays a role in the development of DIGO.	Calcium	39-46	nuclear factor of activated T cells 3	Homo sapiens	47-53	
34109683-15	2021	We propose that the suppression of the calcium-NFATc3-NR4A1 cascade by these three drugs plays a role in the development of DIGO.	Calcium	39-46	nuclear receptor subfamily 4 group A member 1	Homo sapiens	54-59	
34109683-15	2021	We propose that the suppression of the calcium-NFATc3-NR4A1 cascade by these three drugs plays a role in the development of DIGO.	digo	124-128	nuclear factor of activated T cells 3	Homo sapiens	47-53	
34109683-15	2021	We propose that the suppression of the calcium-NFATc3-NR4A1 cascade by these three drugs plays a role in the development of DIGO.	digo	124-128	nuclear receptor subfamily 4 group A member 1	Homo sapiens	54-59