PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34100951-9 2021 In a subsequent study, hepatocytes were transfected with small interfering RNA (siORAI1) or the ORAI1 inhibitor BTP2 for 48 h or 2 h followed by a challenge with the 1.2 mM mixture of fatty acids for 6 h. Compared with control group, silencing or inhibition of ORAI1 led to decreased abundance of fatty acid synthesis (FASN, SREBP1 and ACACA) and ER stress-related proteins in bovine hepatocytes. Fatty Acids 297-307 fatty acid synthase Bos taurus 319-323