PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34023736-4 2021 Notably, when assayed for their biological cell responses mimicking SOCS1 activity, the internal cyclic PS5 analogues demonstrated able to inhibit JAK-mediated tyrosine phosphorylation of STAT1 and to reduce cytokine-induced proinflammatory gene expression, oxidative stress generation and cell migration. Tyrosine 160-168 signal transducer and activator of transcription 1 Homo sapiens 188-193