PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34017375-0 2021 Kinesin family member 2A promotes cancer cell viability, mobility, stemness, and chemoresistance to cisplatin by activating the PI3K/AKT/VEGF signaling pathway in non-small cell lung cancer. Cisplatin 100-109 kinesin family member 2A Homo sapiens 0-24 34017375-0 2021 Kinesin family member 2A promotes cancer cell viability, mobility, stemness, and chemoresistance to cisplatin by activating the PI3K/AKT/VEGF signaling pathway in non-small cell lung cancer. Cisplatin 100-109 vascular endothelial growth factor A Homo sapiens 137-141 34017375-8 2021 KIF2A overexpression elevated proliferation, migration, invasion, stemness, and resistance to cisplatin but did not affect apoptosis or resistance to pemetrexed in A549 cells. Cisplatin 94-103 kinesin family member 2A Homo sapiens 0-5 34017375-9 2021 Furthermore, KIF2A knock-down repressed proliferation, migration, invasion, stemness, and resistance to cisplatin, but not to pemetrexed, and it enhanced apoptosis in NCI-H1299 cells. Cisplatin 104-113 kinesin family member 2A Homo sapiens 13-18 34017375-10 2021 Rescue experiments showed that the PI3K/AKT/VEGF pathway compensated for KIF2A effects on cell functions and sensitivity to cisplatin in A549 and NCI-H1299 cells. Cisplatin 124-133 AKT serine/threonine kinase 1 Homo sapiens 40-43 34017375-10 2021 Rescue experiments showed that the PI3K/AKT/VEGF pathway compensated for KIF2A effects on cell functions and sensitivity to cisplatin in A549 and NCI-H1299 cells. Cisplatin 124-133 vascular endothelial growth factor A Homo sapiens 44-48 34017375-10 2021 Rescue experiments showed that the PI3K/AKT/VEGF pathway compensated for KIF2A effects on cell functions and sensitivity to cisplatin in A549 and NCI-H1299 cells. Cisplatin 124-133 kinesin family member 2A Homo sapiens 73-78 34017375-11 2021 In conclusion, KIF2A advocates NSCLC cell viability, mobility, stemness, and chemoresistance to cisplatin by activating the PI3K/AKT/VEGF signaling pathway. Cisplatin 96-105 kinesin family member 2A Homo sapiens 15-20