PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34002012-10	2021	When cells were treated with metformin (an AMPK activator), the CRBN-induced activation of SMAD3 and upregulation of alpha-SMA and collagen expression were significantly suppressed, suggesting that increased TGF-beta1-induced activation of SMAD3 via CRBN overexpression is associated with AMPKalpha1 inactivation.	Metformin	29-38	actin alpha 2, smooth muscle, aorta	Mus musculus	117-126