PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33995076-7 2021 PRH exposure also significantly increased labetalol metabolism to its UGT1A1-derived glucuronide metabolite in a concentration-dependent manner, which positively correlated with PRH-induced changes in UGT1A1 protein concentrations. Glucuronides 85-96 hematopoietically expressed homeobox Homo sapiens 0-3 33995076-7 2021 PRH exposure also significantly increased labetalol metabolism to its UGT1A1-derived glucuronide metabolite in a concentration-dependent manner, which positively correlated with PRH-induced changes in UGT1A1 protein concentrations. Glucuronides 85-96 hematopoietically expressed homeobox Homo sapiens 178-181 33995076-8 2021 In contrast, PRH did not alter UGT2B7 mRNA levels or protein concentrations in SCHH, and formation of the UGT2B7-derived labetalol glucuronide metabolite was decreased following PRH exposure. Glucuronides 131-142 hematopoietically expressed homeobox Homo sapiens 178-181