PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33990102-6 2021 The alteration of insulin signaling pathways, involved in gastrointestinal manifestations, carcinogenesis, muscle function, cognitive and endocrinological aspects, gain further relevance in the light of recent evidence of metformin efficacy in DM1. Metformin 222-231 DM1 protein kinase Homo sapiens 244-247