PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33920356-3	2021	We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGFR) inhibitor gefitinib, with the focus on ER stress.	Gefitinib	98-107	epidermal growth factor receptor	Homo sapiens	48-80	
33920356-3	2021	We studied here the proapoptotic actions of the Epidermal Growth Factor Receptor (EGFR) inhibitor gefitinib, with the focus on ER stress.	Gefitinib	98-107	epidermal growth factor receptor	Homo sapiens	82-86	
33920356-5	2021	We found that the glioma cell-killing effects of gefitinib involved caspase 3 apoptotic cascades.	Gefitinib	49-58	caspase 3	Homo sapiens	68-77	
33920356-6	2021	Three branches of ER stress, namely Activating Transcription Factor-6 (ATF6), Protein Kinase R (PKR)-Like ER Kinase (PERK), and Inositol-Requiring Enzyme 1 (IRE1), were activated by gefitinib, along with the elevation of intracellular free Ca2+, Reactive Oxygen Species (ROS), and NADPH Oxidase2/4 (NOX2/4).	Gefitinib	182-191	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	128-155	
33920356-8	2021	Genetic, pharmacological, and biochemical studies further indicated an active ROS/ER stress/Ask1/JNK/Noxa axis causing the glioma apoptosis induced by gefitinib.	Gefitinib	151-160	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	92-96	
33920356-8	2021	Genetic, pharmacological, and biochemical studies further indicated an active ROS/ER stress/Ask1/JNK/Noxa axis causing the glioma apoptosis induced by gefitinib.	Gefitinib	151-160	mitogen-activated protein kinase 8	Homo sapiens	97-100	
33920356-8	2021	Genetic, pharmacological, and biochemical studies further indicated an active ROS/ER stress/Ask1/JNK/Noxa axis causing the glioma apoptosis induced by gefitinib.	Gefitinib	151-160	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	101-105