PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3390448-2	1988	HMG-CoA reductase mRNA levels increased within 2 h of stimulation and remained elevated for at least 6 h. Treatment of granulosa cells with 25-hydroxycholesterol, a soluble cholesterol analogue, in combination with aminoglutethimide to block conversion of cellular sterols to pregnenolone, resulted in suppression of HMG-CoA reductase mRNA.	25-hydroxycholesterol	140-161	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	0-17	
3390448-2	1988	HMG-CoA reductase mRNA levels increased within 2 h of stimulation and remained elevated for at least 6 h. Treatment of granulosa cells with 25-hydroxycholesterol, a soluble cholesterol analogue, in combination with aminoglutethimide to block conversion of cellular sterols to pregnenolone, resulted in suppression of HMG-CoA reductase mRNA.	25-hydroxycholesterol	140-161	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	317-334	
3390448-3	1988	When cells were stimulated with 8-bromo-cAMP in the presence of 25-hydroxycholesterol and aminoglutethimide, the increase in HMG-CoA reductase mRNA provoked by the tropic agent was markedly attenuated.	25-hydroxycholesterol	64-85	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	125-142