PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33888130-0 2021 BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting "Undruggable" Myc-pathway genes. omega-N-Allylarginine 21-24 bromodomain containing 4 Homo sapiens 0-4 33888130-0 2021 BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting "Undruggable" Myc-pathway genes. omega-N-Allylarginine 21-24 MYC proto-oncogene, bHLH transcription factor Homo sapiens 101-104 33888130-9 2021 BRD4, BRD3 and BRD2 proteins were detected by western blot in cells treated with ARV-825. omega-N-Allylarginine 81-84 bromodomain containing 4 Homo sapiens 0-4 33888130-9 2021 BRD4, BRD3 and BRD2 proteins were detected by western blot in cells treated with ARV-825. omega-N-Allylarginine 81-84 bromodomain containing 3 Homo sapiens 6-10 33888130-9 2021 BRD4, BRD3 and BRD2 proteins were detected by western blot in cells treated with ARV-825. omega-N-Allylarginine 81-84 bromodomain containing 2 Homo sapiens 15-19 33888130-18 2021 In the T-ALL xenograft model, ARV-825 significantly reduced tumor growth and led to the dysregulation of Ki67 and cleaved caspase 3. omega-N-Allylarginine 30-33 caspase 3 Homo sapiens 122-131