PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33866495-0	2021	Nicotinamide mononucleotide and melatonin counteract myocardial ischemia-reperfusion injury by activating SIRT3/FOXO1 and reducing apoptosis in aged male rats.	Melatonin	32-41	forkhead box O1	Rattus norvegicus	112-117	
33866495-11	2021	Melatonin and NMN upregulated the gene expression of Bcl-2, SIRT3, and FOXO1 and downregulated the gene expression of Bax, and Caspase-3, in comparison to the IR group.	Melatonin	0-9	forkhead box O1	Rattus norvegicus	71-76	
33866495-14	2021	These findings indicate that the combined administration of NMN and melatonin can protect the aged heart against IR injury by decreasing apoptosis and activating the SIRT3/FOXO1 pathway.	Melatonin	68-77	forkhead box O1	Rattus norvegicus	172-177