PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33857626-0 2021 Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo. Reactive Oxygen Species 70-73 tumor protein p53 Homo sapiens 83-86 33857626-8 2021 Specifically, NOX4 knockdown inhibited NaF-induced the activation of p53/DR5 axis by reducing NOX4-derived ROS production. Reactive Oxygen Species 107-110 tumor protein p53 Homo sapiens 69-72