PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33838472-3	2021	Through pharmacological or genetic inhibition of SOD1, we show that elevated intracellular superoxide (O2-) mediates sustained IKK phosphorylation, and induces downstream degradation of IkappaBalpha, leading to the nuclear localization and transcriptional activation of NF-kappaB.	Superoxides	91-101	superoxide dismutase 1	Homo sapiens	49-53