PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phospholipids 13-26 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phospholipids 13-26 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phosphatidylcholines 27-46 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phosphatidylcholines 27-46 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. phosphatidylethanolamine 51-75 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. phosphatidylethanolamine 51-75 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. phosphatidylethanolamine 77-79 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. phosphatidylethanolamine 77-79 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Choline 39-46 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Choline 39-46 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Ethanolamine 63-75 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Ethanolamine 63-75 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Diglycerides 291-305 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Diglycerides 291-305 cut like homeobox 1 Homo sapiens 128-131 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phospholipids 13-25 cut like homeobox 1 Homo sapiens 112-115 33789160-1 2021 The membrane phospholipids phosphatidylcholine and phosphatidylethanolamine (PE) are synthesized de novo by the CDP-choline and CDP-ethanolamine (Kennedy) pathway, in which the extracellular substrates choline and ethanolamine are transported into the cell, phosphorylated, and coupled with diacylglycerol to form the final phospholipid product. Phospholipids 13-25 cut like homeobox 1 Homo sapiens 128-131 33789160-4 2021 We report a novel function of CTL1 and CTL2 in ethanolamine transport. Ethanolamine 47-59 solute carrier family 44 member 1 Homo sapiens 30-34 33789160-4 2021 We report a novel function of CTL1 and CTL2 in ethanolamine transport. Ethanolamine 47-59 solute carrier family 44 member 2 Homo sapiens 39-43 33789160-5 2021 Using the lack or the gain of gene function in combination with specific antibodies and transport inhibitors we established two distinct ethanolamine transport systems of a high affinity, mediated by CTL1, and of a low affinity, mediated by CTL2. Ethanolamine 137-149 solute carrier family 44 member 1 Homo sapiens 200-204 33789160-5 2021 Using the lack or the gain of gene function in combination with specific antibodies and transport inhibitors we established two distinct ethanolamine transport systems of a high affinity, mediated by CTL1, and of a low affinity, mediated by CTL2. Ethanolamine 137-149 solute carrier family 44 member 2 Homo sapiens 241-245 33789160-8 2021 The lack of CTL1 in M2 cells reduced the ethanolamine transport, the flux through the CDP-ethanolamine Kennedy pathway, and PE synthesis. Ethanolamine 41-53 solute carrier family 44 member 1 Homo sapiens 12-16 33789160-8 2021 The lack of CTL1 in M2 cells reduced the ethanolamine transport, the flux through the CDP-ethanolamine Kennedy pathway, and PE synthesis. phosphatidylethanolamine 124-126 solute carrier family 44 member 1 Homo sapiens 12-16 33789160-9 2021 In contrast, overexpression of CTL1 in M2 cells improved ethanolamine transport and PE synthesis. Ethanolamine 57-69 solute carrier family 44 member 1 Homo sapiens 31-35 33789160-9 2021 In contrast, overexpression of CTL1 in M2 cells improved ethanolamine transport and PE synthesis. phosphatidylethanolamine 84-86 solute carrier family 44 member 1 Homo sapiens 31-35 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. Ethanolamine 72-84 solute carrier family 44 member 1 Homo sapiens 33-37 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. Ethanolamine 72-84 solute carrier family 44 member 2 Homo sapiens 42-46 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. phosphatidylethanolamine 163-165 solute carrier family 44 member 1 Homo sapiens 33-37 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. phosphatidylethanolamine 163-165 solute carrier family 44 member 2 Homo sapiens 42-46 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. Ethanolamine 235-247 solute carrier family 44 member 1 Homo sapiens 33-37 33789160-10 2021 These data firmly establish that CTL1 and CTL2 are the first identified ethanolamine transporters in whole cells and mitochondria, with intrinsic roles in de novo PE synthesis by the Kennedy pathway and intracellular redistribution of ethanolamine. Ethanolamine 235-247 solute carrier family 44 member 2 Homo sapiens 42-46