PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33753114-9	2021	After co-culture of Hep3B cells and PBMCs, curcumin had a synergistic effect with anti-PD-1 to slow Hep3B cell proliferation, activate lymphocytes, inhibit immune evasion, and down-regulate TGF-beta1 expression.	Curcumin	43-51	transforming growth factor beta 1	Homo sapiens	190-199	
33753114-10	2021	Functionally, curcumin inhibited thrombin to reduce P300-induced histone acetylation in the TGF-beta1 promoter region, and anti-PD-1 suppressed binding of PD-1 and PD-L1 to promote immune activity; the combination of the two showed better in vitro anti-cancer effects.	Curcumin	14-22	transforming growth factor beta 1	Homo sapiens	92-101