PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33654003-6 2021 RESULTS: GWAS verified that CYP3A5*3 is the only common variant associated with TAC PK variability in Koreans. Tacrolimus 80-83 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 28-34 33654003-7 2021 We detected several CYP3A5 and CYP3A4 rare variants which could potentially affect TAC metabolism. Tacrolimus 83-86 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 20-26 33654003-10 2021 Gene-based association tests in the 61 absorption, distribution, metabolism, and excretion (ADME) genes revealed that CYP1A1 are associated with additional TAC PK variability: CYP1A1 rare variant carriers among CYP3A5 poor metabolizers showed lower TAC trough levels than the noncarrier controls. Tacrolimus 156-159 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 211-217