PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33652374-0	2021	Theophylline alleviates gentamicin-induced cytotoxicity to sensory hair cells by maintaining HDAC2 expression.	Theophylline	0-12	histone deacetylase 2	Homo sapiens	93-98	
33652374-0	2021	Theophylline alleviates gentamicin-induced cytotoxicity to sensory hair cells by maintaining HDAC2 expression.	Gentamicins	24-34	histone deacetylase 2	Homo sapiens	93-98	
33652374-3	2021	Our study aimed to examine the potential effects of theophylline, an HDAC2 agonist, on gentamicin-induced cytotoxicity to sensory hair cells.	Theophylline	52-64	histone deacetylase 2	Homo sapiens	69-74	
33652374-3	2021	Our study aimed to examine the potential effects of theophylline, an HDAC2 agonist, on gentamicin-induced cytotoxicity to sensory hair cells.	Gentamicins	87-97	histone deacetylase 2	Homo sapiens	69-74	
33652374-9	2021	HDAC2 expression was downregulated by gentamicin, which could be restored by theophylline.	Gentamicins	38-48	histone deacetylase 2	Homo sapiens	0-5	
33652374-9	2021	HDAC2 expression was downregulated by gentamicin, which could be restored by theophylline.	Theophylline	77-89	histone deacetylase 2	Homo sapiens	0-5	
33652374-10	2021	HDAC2 silencing in HEI-OC1 cells negated the beneficial effect of theophylline against gentamicin-induced growth defect and apoptosis activation.	Theophylline	66-78	histone deacetylase 2	Homo sapiens	0-5	
33652374-10	2021	HDAC2 silencing in HEI-OC1 cells negated the beneficial effect of theophylline against gentamicin-induced growth defect and apoptosis activation.	Gentamicins	87-97	histone deacetylase 2	Homo sapiens	0-5	
33652374-11	2021	Theophylline protects sensory hair cells from gentamicin ototoxicity by maintaining HDAC2 expression.	Theophylline	0-12	histone deacetylase 2	Homo sapiens	84-89	
33652374-12	2021	Our study thereby discovers a critical role of HDAC2 in gentamicin-induced ototoxicity, which could shine light on potential therapeutic options for treatment against sensorineural hearing loss.	Gentamicins	56-66	histone deacetylase 2	Homo sapiens	47-52