PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33625942-0	2021	Metformin Alleviates Cisplatin-Induced Ototoxicity by Autophagy Induction Possibly via the AMPK/FOXO3a Pathway.	Metformin	0-9	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	91-95	
33625942-10	2021	Notably, metformin activated autophagy and increased the expression levels of the adenosine monophosphate-activated protein kinase (AMPK) and the transcription factor Forkhead box protein O3 (FOXO3a), while cells with AMPK silencing displayed otherwise.	Metformin	9-18	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	82-130	
33625942-10	2021	Notably, metformin activated autophagy and increased the expression levels of the adenosine monophosphate-activated protein kinase (AMPK) and the transcription factor Forkhead box protein O3 (FOXO3a), while cells with AMPK silencing displayed otherwise.	Metformin	9-18	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	132-136	
33625942-10	2021	Notably, metformin activated autophagy and increased the expression levels of the adenosine monophosphate-activated protein kinase (AMPK) and the transcription factor Forkhead box protein O3 (FOXO3a), while cells with AMPK silencing displayed otherwise.	Metformin	9-18	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	218-222	
33625942-11	2021	Our findings indicate that metformin alleviates cisplatin-induced ototoxicity possibly through AMPK/FOXO3a-mediated autophagy machinery.	Metformin	27-36	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	95-99