PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33573583-7 2021 Remarkably, the lower dose of ALA modified ERUPR and supported the reduction of behavioral deficits in youngest adults through enhancement of GRP87/Bip, reduction of ATF6, downregulation of PERK-ATF4 pathway, and activation of the IRE1-XBP1 pathway. Thioctic Acid 30-33 activating transcription factor 4 Homo sapiens 195-199 33573583-8 2021 On the other hand, only a higher dose of ALA was able to affect the ERUPR via moderation of PERK-ATF4 signaling in the oldest adults. Thioctic Acid 41-44 activating transcription factor 4 Homo sapiens 97-101