PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33539025-5 2021 These include mechanisms that were conserved during evolution but have gained special features in multicellular eukaryotes, such as pathways regulated by eukaryotic translation initiation factor 2 (eIF-2)-alpha kinase (GCN2, also named general control nonderepressible 2 kinase), 5"-adenosine monophosphate (AMP)-activated protein kinase (AMPK) and target of rapamycin (TOR).The interplay between IDO-1 and above-mentioned pathway seems to be highly context dependent. Adenosine 283-292 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 339-343