PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33486250-8	2021	Curcumin significantly increased phosphorylation of Akt [Thr308] and attenuated fluoride-mediated caspase-3 cleavage and DNA damage marker gammaH2AX expression.	Curcumin	0-8	AKT serine/threonine kinase 1	Homo sapiens	52-55	
33486250-9	2021	Curcumin-mediated attenuation of caspase-3 activation was reversed by Akt inhibitor LY294002 (LY).	Curcumin	0-8	AKT serine/threonine kinase 1	Homo sapiens	70-73	
33486250-11	2021	These results suggest that curcumin inhibited fluoride-mediated apoptosis via Akt activation, but DNA damage was suppressed by other pathways.	Curcumin	27-35	AKT serine/threonine kinase 1	Homo sapiens	78-81	
33486250-16	2021	These results suggest that curcumin-induced Ac-p53 and p21 led to cell cycle arrest, while curcumin attenuated fluoride-mediated apoptosis via activation of Akt and suppressed fluoride-mediated DNA damage.	Curcumin	91-99	AKT serine/threonine kinase 1	Homo sapiens	157-160