PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33432012-1 2021 Tacrolimus (TAC) pharmacokinetics is influenced by the donor CYP3A5 genotype and the age of pediatric liver recipients. Tacrolimus 0-10 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 61-67 33432012-1 2021 Tacrolimus (TAC) pharmacokinetics is influenced by the donor CYP3A5 genotype and the age of pediatric liver recipients. Tacrolimus 12-15 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 61-67 33432012-6 2021 TAC concentration/weight-adjusted dose ratio was significantly lower in recipients from CYP3A5*1/*3 donors or with extra-large (GRWR > 5%) or large (GRWR 3-5%) grafts. Tacrolimus 0-3 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 88-94 33432012-9 2021 In conclusion, TAC starting dose could be guided according to the donor CYP3A5 genotype and GRWR, allowing for a quicker achievement of target concentrations and eventually reducing the risk of rejection. Tacrolimus 15-18 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 72-78