PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33361598-1	2021	BACKGROUND: Berberine (BBR) plays a neuroprotective role in the pathogenesis of Alzheimer"s disease (AD), inhibiting amyloid-beta (Abeta) production and promoting Abeta clearance.	Berberine	12-21	amyloid beta (A4) precursor protein	Mus musculus	131-136	
33361598-1	2021	BACKGROUND: Berberine (BBR) plays a neuroprotective role in the pathogenesis of Alzheimer"s disease (AD), inhibiting amyloid-beta (Abeta) production and promoting Abeta clearance.	Berberine	12-21	amyloid beta (A4) precursor protein	Mus musculus	163-168	
33361598-1	2021	BACKGROUND: Berberine (BBR) plays a neuroprotective role in the pathogenesis of Alzheimer"s disease (AD), inhibiting amyloid-beta (Abeta) production and promoting Abeta clearance.	Berberine	23-26	amyloid beta (A4) precursor protein	Mus musculus	131-136	
33361598-1	2021	BACKGROUND: Berberine (BBR) plays a neuroprotective role in the pathogenesis of Alzheimer"s disease (AD), inhibiting amyloid-beta (Abeta) production and promoting Abeta clearance.	Berberine	23-26	amyloid beta (A4) precursor protein	Mus musculus	163-168	
33361598-4	2021	This work focused on whether BBR regulates the production and clearance of ribosylation-induced Abeta pathology via inhibiting mTOR signaling.	Berberine	29-32	amyloid beta (A4) precursor protein	Mus musculus	96-101	
33361598-5	2021	OBJECTIVE: To explore whether BBR ameliorates ribosylation-induced Abeta pathology in APP/PS1 mice.	Berberine	30-33	amyloid beta (A4) precursor protein	Mus musculus	67-72	
33361598-11	2021	BBR reduces the activity of BACE1 and gamma-secretase induced by D-ribose, and enhances Abeta-degrading enzymes and Neprilysin, and inhibits the expression of Abeta in APP/PS1 mice.	Berberine	0-3	amyloid beta (A4) precursor protein	Mus musculus	88-93	
33361598-11	2021	BBR reduces the activity of BACE1 and gamma-secretase induced by D-ribose, and enhances Abeta-degrading enzymes and Neprilysin, and inhibits the expression of Abeta in APP/PS1 mice.	Berberine	0-3	amyloid beta (A4) precursor protein	Mus musculus	159-164	
33361598-12	2021	CONCLUSION: BBR ameliorates ribosylation-induced Abeta pathology via inhibiting mTOR/p70S6K signaling and improves spatial learning and memory of the APP/PS1 mice.	Berberine	12-15	amyloid beta (A4) precursor protein	Mus musculus	49-54