PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33360082-3 2021 Aiming at the elucidation of MAO-B inhibitors with 1,3,4-oxadiazole scaffolds, we make a comprehensive update on the new and old chemical methods employed for the synthesis of the unsymmetrical oxadiazole derivatives that lead to high yield compounds. Oxadiazoles 57-67 monoamine oxidase B Homo sapiens 29-34 33360082-4 2021 We summarize a state of the selective MAO-B inhibitors with oxadiazole scaffold, describing the results, structures, structure-activity relationships (SARs) and medicinal chemistry strategies over the years. Oxadiazoles 60-70 monoamine oxidase B Homo sapiens 38-43 33360082-5 2021 The analysis of the recent papers would facilitate tracking the increasing number of oxadiazole derivatives as new chemical spaces with MAO-B inhibitory potential designed to ensure the safe use of the compounds and elimination of the unwanted drug-drug interactions. Oxadiazoles 85-95 monoamine oxidase B Homo sapiens 136-141