PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33309746-7	2021	Escin ameliorated the increasing levels of RhoA, ROCK1, nuclear NF-kappaB and the decreasing expression of IkappaBalpha, cytosolic NF-kappaB, occludin, claudin-5 in the ICH group.	Escin	0-5	ras homolog family member A	Mus musculus	43-47	
33309746-8	2021	IL-1beta administration blocked not only escin-mediated increases of IkappaBalpha, cytosolic NF-kappaB, occludin, and claudin-5, but also escin-caused decreases of RhoA, ROCK1, and nuclear NF-kappaB.	Escin	138-143	ras homolog family member A	Mus musculus	164-168	
33309746-9	2021	The results indicate that escin improves neurological outcomes and the BBB function in ICH mice, which is associated with attenuating ICH-induced peripheral system inflammation, and therefore, inhibiting IL-1beta/RhoA/NF-kappaB signaling pathway in BBB, at least in part.	Escin	26-31	ras homolog family member A	Mus musculus	213-217