PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33252269-0 2020 Association of ABCB1 and CYP450 Gene Polymorphisms and their DNA Methylation Status with Steroid-Induced Osteonecrosis of the Femoral Head in the Chinese Population. Steroids 89-96 ATP binding cassette subfamily B member 1 Homo sapiens 15-20 33252269-3 2020 The aim of this study was to investigate the relationship between polymorphisms of the drug-metabolizing enzyme gene, cytochrome P450 (CYP450), and the drug transporter gene, ATP-binding cassette subfamily B member 1 (ABCB1), as well as their DNA methylation status with the pathogenesis of steroid-induced ONFH. Steroids 291-298 ATP binding cassette subfamily B member 1 Homo sapiens 218-223 33252269-9 2020 In the genetic model analysis, the T allele of the rs2032582 locus in the ABCB1 gene was associated with a reduced risk of steroid-induced ONFH under the dominant model (OR = 0.465, 95% CI: 0.223-0.972, p = 0.042). Steroids 123-130 ATP binding cassette subfamily B member 1 Homo sapiens 74-79 33252269-12 2020 Conclusions: This study provides evidence for two steroid-induced ONFH susceptibility genes (ABCB1, CYP450) in the Han Chinese population. Steroids 50-57 ATP binding cassette subfamily B member 1 Homo sapiens 93-98