PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33220275-0 2021 Metformin reduces proteinuria in spontaneously hypertensive rats by activating the HIF-2alpha-VEGF-A pathway. Metformin 0-9 endothelial PAS domain protein 1 Rattus norvegicus 83-93 33220275-0 2021 Metformin reduces proteinuria in spontaneously hypertensive rats by activating the HIF-2alpha-VEGF-A pathway. Metformin 0-9 vascular endothelial growth factor A Rattus norvegicus 94-100 33220275-8 2021 Metformin increased the production of vascular endothelial growth factor (VEGF)-A in rat kidneys and cultured rat podocytes. Metformin 0-9 vascular endothelial growth factor A Rattus norvegicus 74-78 33220275-9 2021 Metformin activated hypoxia-inducible factor-2alpha (Hif-2alpha) in response to VEGF but did not affect Hif-1alpha in rat kidneys and cultured rat podocytes. Metformin 0-9 endothelial PAS domain protein 1 Rattus norvegicus 20-51 33220275-9 2021 Metformin activated hypoxia-inducible factor-2alpha (Hif-2alpha) in response to VEGF but did not affect Hif-1alpha in rat kidneys and cultured rat podocytes. Metformin 0-9 endothelial PAS domain protein 1 Rattus norvegicus 53-63 33220275-9 2021 Metformin activated hypoxia-inducible factor-2alpha (Hif-2alpha) in response to VEGF but did not affect Hif-1alpha in rat kidneys and cultured rat podocytes. Metformin 0-9 vascular endothelial growth factor A Rattus norvegicus 80-84 33220275-10 2021 Metformin reduced the proteinuria induced by long-term high blood pressure in vivo and increased the VEGF-A production in rat kidneys and cultured rat podocytes, probably by activating the Hif-2alpha-VEGF signaling pathway. Metformin 0-9 vascular endothelial growth factor A Rattus norvegicus 101-107 33220275-10 2021 Metformin reduced the proteinuria induced by long-term high blood pressure in vivo and increased the VEGF-A production in rat kidneys and cultured rat podocytes, probably by activating the Hif-2alpha-VEGF signaling pathway. Metformin 0-9 endothelial PAS domain protein 1 Rattus norvegicus 189-199 33220275-10 2021 Metformin reduced the proteinuria induced by long-term high blood pressure in vivo and increased the VEGF-A production in rat kidneys and cultured rat podocytes, probably by activating the Hif-2alpha-VEGF signaling pathway. Metformin 0-9 vascular endothelial growth factor A Rattus norvegicus 101-105