PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33192276-0 2020 Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons. 3-Hydroxybutyric Acid 0-20 brain derived neurotrophic factor Homo sapiens 30-34 33192276-3 2020 Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. 3-Hydroxybutyric Acid 21-25 brain derived neurotrophic factor Homo sapiens 35-68 33192276-3 2020 Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. 3-Hydroxybutyric Acid 21-25 brain derived neurotrophic factor Homo sapiens 70-74 33192276-3 2020 Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. 3-Hydroxybutyric Acid 21-25 brain derived neurotrophic factor Homo sapiens 151-155 33192276-6 2020 These results indicate that BHBA regulates cellular signaling and multiple histone modifications to cooperatively modulate BDNF, suggesting a wide range of regulatory effects of BHBA in the central nervous system. 3-Hydroxybutyric Acid 28-32 brain derived neurotrophic factor Homo sapiens 123-127 33192276-6 2020 These results indicate that BHBA regulates cellular signaling and multiple histone modifications to cooperatively modulate BDNF, suggesting a wide range of regulatory effects of BHBA in the central nervous system. 3-Hydroxybutyric Acid 178-182 brain derived neurotrophic factor Homo sapiens 123-127