PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33132314-4 2020 The effect of germacrone on organic cation transporter 2 (OCT2) which is a transporter responsible for cisplatin uptake was determined. germacrone 14-24 solute carrier family 22 member 2 Homo sapiens 28-56 33132314-4 2020 The effect of germacrone on organic cation transporter 2 (OCT2) which is a transporter responsible for cisplatin uptake was determined. germacrone 14-24 solute carrier family 22 member 2 Homo sapiens 58-62 33132314-5 2020 Germacrone showed an inhibitory effect on OCT2-mediated methyl-4-phenylpyridinium acetate (3H-MPP+) uptake with IC50 of 15 microM with less effect on OCT1. germacrone 0-10 solute carrier family 22 member 2 Homo sapiens 42-46 33132314-5 2020 Germacrone showed an inhibitory effect on OCT2-mediated methyl-4-phenylpyridinium acetate (3H-MPP+) uptake with IC50 of 15 microM with less effect on OCT1. germacrone 0-10 solute carrier family 22 member 1 Homo sapiens 150-154 33132314-7 2020 In conclusion, germacrone prevents cisplatin-induced toxicity in renal proximal tubular cells via inhibition OCT2 transport function and reducing cisplatin accumulation. germacrone 15-25 solute carrier family 22 member 2 Homo sapiens 109-113