PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33099954-0 2020 Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Metformin 0-9 thymoma viral proto-oncogene 1 Mus musculus 59-62 33099954-1 2020 PURPOSE: To investigate the influences of metformin on the proliferation and apoptosis of mouse melanoma B16 cells through regulating the phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway. Metformin 42-51 thymoma viral proto-oncogene 1 Mus musculus 201-204 33099954-9 2020 CONCLUSIONS: Metformin can inhibit the proliferation of mouse melanoma B16 cells and induce their apoptosis probably through its regulation on the PI3K/AKT/mTOR signaling pathway in cells. Metformin 13-22 thymoma viral proto-oncogene 1 Mus musculus 152-155