PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33093270-0 2020 AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis. allyl isothiocyanate 0-4 NFE2 like bZIP transcription factor 2 Homo sapiens 119-123 33093270-5 2020 The expression of DJ-1, Nrf2, HO-1, and MRP1 was significantly decreased in the wild type model group, while the expression of each protein was significantly increased after administration of AITC. allyl isothiocyanate 192-196 NFE2 like bZIP transcription factor 2 Homo sapiens 24-28 33093270-6 2020 Silencing the expression of DJ-1 in 16HBE cells accelerated CSE-induced protein degradation, and significantly attenuated the AITC-induced mRNA and protein expression of Nrf2 and MRP1. allyl isothiocyanate 126-130 NFE2 like bZIP transcription factor 2 Homo sapiens 170-174 33093270-7 2020 The present study describes a novel mechanism by which AITC induces MRP1 expression by protecting against CS/CSEmediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis. allyl isothiocyanate 55-59 NFE2 like bZIP transcription factor 2 Homo sapiens 173-177