PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33068587-0 2021 Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. yangonin 0-8 microRNA 194-1 Mus musculus 60-67 33068587-0 2021 Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. yangonin 0-8 nuclear receptor subfamily 1 group H member 4 Homo sapiens 68-71 33068587-0 2021 Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. Ethanol 18-25 microRNA 194-1 Mus musculus 60-67 33068587-0 2021 Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. Ethanol 18-25 nuclear receptor subfamily 1 group H member 4 Homo sapiens 68-71 33068587-4 2021 Yangonin (Yan), a bioactive compound extract from Kava, has been reported to exert hepatoprotective effects via Farnesoid X receptor (FXR) activation. yangonin 0-8 nuclear receptor subfamily 1 group H member 4 Homo sapiens 134-137 33068587-7 2021 We detected miR-194 levels in ethanol-induced LO2 cells and male C57BL/6 mice by quantitative real-time PCR. Ethanol 30-37 microRNA 194-1 Mus musculus 12-19 33068587-12 2021 We observed that Yan significantly inhibited ethanol-induced cellular senescence via FXR activation (P < 0.05). Ethanol 45-52 nuclear receptor subfamily 1 group H member 4 Homo sapiens 85-88 33068587-14 2021 MiR-194 was upregulated in the alcoholic liver disease, which was significantly suppressed by Yan (P < 0.05). yangonin 94-97 microRNA 194-1 Mus musculus 0-7 33068587-16 2021 In summary, these aggregated data demonstrate that Yan alleviates chronic ethanol-induced liver injury through inhibition of cellular senescence via regulating miR-194/FXR axis. Ethanol 74-81 microRNA 194-1 Mus musculus 160-167 33068587-16 2021 In summary, these aggregated data demonstrate that Yan alleviates chronic ethanol-induced liver injury through inhibition of cellular senescence via regulating miR-194/FXR axis. Ethanol 74-81 nuclear receptor subfamily 1 group H member 4 Homo sapiens 168-171