PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32863909-0	2020	GLI1 activation is a key mechanism of erlotinib resistance in human non-small cell lung cancer.	Erlotinib Hydrochloride	38-47	GLI family zinc finger 1	Homo sapiens	0-4	
32863909-6	2020	In the present study, the role of GLI1 in erlotinib resistance was investigated.	Erlotinib Hydrochloride	42-51	GLI family zinc finger 1	Homo sapiens	34-38	
32863909-8	2020	GLI1 mRNA expression levels were found to be positively correlated with the IC50 of erlotinib in 15 non-small cell lung cancer (NSCLC) cell lines.	Erlotinib Hydrochloride	84-93	GLI family zinc finger 1	Homo sapiens	0-4	
32863909-9	2020	The downregulation of GLI1 using siRNA sensitized lung cancer cells to the erlotinib treatment, whereas the overexpression of GLI1 increased the survival of lung cancer cells in the presence of erlotinib, indicating that Hh/GLI activation may play a critical role in the development of TKI resistance in lung cancer.	Erlotinib Hydrochloride	75-84	GLI family zinc finger 1	Homo sapiens	22-26	
32863909-9	2020	The downregulation of GLI1 using siRNA sensitized lung cancer cells to the erlotinib treatment, whereas the overexpression of GLI1 increased the survival of lung cancer cells in the presence of erlotinib, indicating that Hh/GLI activation may play a critical role in the development of TKI resistance in lung cancer.	Erlotinib Hydrochloride	194-203	GLI family zinc finger 1	Homo sapiens	126-130	
32863909-10	2020	Combined treatment with erlotinib and a GLI1 inhibitor reduced the cell viability synergistically.	Erlotinib Hydrochloride	24-33	GLI family zinc finger 1	Homo sapiens	40-44	
32863909-11	2020	A retrospective study of patients with NSCLC treated with erlotinib revealed that those with a high IHC score for GLI1 protein expression had a poorer prognosis.	Erlotinib Hydrochloride	58-67	GLI family zinc finger 1	Homo sapiens	114-118